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Vectors for Rat Zap70

Gene Information

  • Offical Gene Symbol Zap70
  • Species Rat (Rattus norvegicus)
  • Offical Full Name zeta chain of T cell receptor associated protein kinase 70
  • Other Aliases Srk
  • Other Desigations tyrosine-protein kinase ZAP-70; syk-related protein tyrosine kinase; zeta-chain (TCR) associated protein kinase 70
  • Gene Type protein-coding
  • Summary
    Predicted to enable several functions, including ATP binding activity; non-membrane spanning protein tyrosine kinase activity; and phosphotyrosine residue binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within several processes, including T cell selection; positive regulation of alpha-beta T cell activation; and protein phosphorylation. Predicted to be located in cell-cell junction; cytosol; and immunological synapse. Predicted to be part of T cell receptor complex. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to colocalize with membrane raft. Human ortholog(s) of this gene implicated in immunodeficiency 48 and severe combined immunodeficiency. Orthologous to human ZAP70 (zeta chain of T cell receptor associated protein kinase 70). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 301348
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Rat Zap70(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Zap70 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Rat Zap70 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Rat Zap70 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Rat Zap70 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Rat Zap70 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Zap70 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Rat Zap70 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Rat Zap70 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Rat Zap70 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Zap70 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Rat Zap70 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Rat Zap70 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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