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Vectors for Rat Neu4

Gene Information

  • Offical Gene Symbol Neu4
  • Species Rat (Rattus norvegicus)
  • Offical Full Name neuraminidase 4
  • Other Aliases -
  • Other Desigations sialidase-4
  • Gene Type protein-coding
  • Summary
    Predicted to enable exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. Predicted to be involved in several processes, including ganglioside catabolic process; glycoprotein catabolic process; and negative regulation of neuron projection development. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; lysosome; and mitochondrial membrane. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human NEU4 (neuraminidase 4). [provided by Alliance of Genome Resources, Apr 2022] Annotation information: Note: Neu4 (GeneID: 316642) is annotated incorrectly on Rnor_6.0 but correctly on Rn_Celera. Annotation of Neu4 on Rn_Celera is supported by synteny with human and mouse and is instead annotated as NEWGENE_1308624 (GeneID: 103690047) on Rnor_6.0. Additionally, the locus annotated as Neu4 on Rnor_6.0 likely represents a duplicate placement of this locus that lacks support by the syntenic region in mouse and human. BLASTing Neu4 NM_001108234.1 and NEWGENE_1308624 XM_006245535.2 against the rat genome (Annotation Release 105) shows best hits to NC_005108.4 on Rnor_6.0 (at locations where Neu4 and NEWGENE_1308624 are annotated) and AC_000077.1 on Rn_Celera where Neu4 is annotated. 2-sequence BLAST of Neu4 NM_001108234.1 against NEWGENE_1308624 XM_006245535.2 shows high sequence identity (66% coverage, 100% identity). BLASTing Neu4 underlying component AC118069.8 against the rat genome shows best hit to NC_005108.4 on Rnor_6.0 where Neu4 is annotated (hitting itself) and where NEWGENE_1308624 is annotated. 2-sequence BLAST of Neu4 underlying component AC118069.8 against NEWGENE_1308624 underlying component AABR07068355.1 shows 99% sequence identity across ~96 kb. [27 Mar 2015]
  • NCBI Gene ID 316642
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Neu4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Neu4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Neu4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Neu4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Neu4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Neu4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Neu4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Rat Neu4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Rat Neu4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Rat Neu4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Neu4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
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Rat Neu4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Rat Neu4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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