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Vectors for Rat Ndp

Gene Information

  • Offical Gene Symbol Ndp
  • Species Rat (Rattus norvegicus)
  • Offical Full Name norrin cystine knot growth factor NDP
  • Other Aliases Ndph; RGD1563968
  • Other Desigations norrin; NDP, norrin cystine knot growth factor; Norrie disease (pseudoglioma); Norrie disease homolog; norrin-like
  • Gene Type protein-coding
  • Summary
    Predicted to enable cytokine activity; frizzled binding activity; and protein homodimerization activity. Involved in decidualization. Predicted to be located in cell surface; collagen-containing extracellular matrix; and extracellular space. Predicted to be active in extracellular matrix. Human ortholog(s) of this gene implicated in Norrie disease; X-linked exudative vitreoretinopathy 2; and retinopathy of prematurity. Orthologous to human NDP (norrin cystine knot growth factor NDP). [provided by Alliance of Genome Resources, Apr 2022] Annotation information: Note: Ndp was annotated incorrectly on Rnor_6.0 (Annotation Release 105) but correctly on Rn_Celera. Annotation of Ndp on Rn_Celera is supported by synteny with human and mouse and this locus is instead annotated as LOC100909913 on Rnor_6.0. Additionally, the locus annotated as Ndp on Rnor_6.0 represents a duplicate placement of this locus and this annotation lacks support by the syntenic region in mouse and human. BLASTing Ndp NM_001108814.1 against the rat genome (Annotation Release 105) shows best hits to the locations where both Ndp and LOC100909913 are annotated on Rnor_6.0 (NC_005120.4, 100% identity at each location) and where Ndp is annotated on Rn_Celera (AC_000089.1, 100% identity). BLASTing LOC100909913 XM_003751998.3 against the rat genome (Annotation Release 105) shows best hits to the locations where both Ndp and LOC100909913 are annotated on Rnor_6.0 (NC_005120.4, 100% identity at each location) and where Ndp is annotated on Rn_Celera (AC_000089.1, 100% identity). 2-sequence BLAST of Ndp NM_001108814.1 against LOC100909913 XM_003751998.3 shows high sequence identity (100% coverage, 100% identity). 2-sequence BLAST of Ndp underlying component AC097257.7 against the LOC100909913 underlying component AABR07073515.1 (both on Rnor_6.0) shows high sequence identity (99%) across ~67 kb. [26 Mar 2015]
  • NCBI Gene ID 363443
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Ndp(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Ndp expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Ndp expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Ndp expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Ndp expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Ndp expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Ndp shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Rat Ndp shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Rat Ndp shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Rat Ndp shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Ndp CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Ndp CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Rat Ndp CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
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