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Vectors for Mouse Nedd4l

Gene Information

  • Offical Gene Symbol Nedd4l
  • Species Mouse (Mus musculus)
  • Offical Full Name neural precursor cell expressed, developmentally down-regulated gene 4-like
  • Other Aliases 1300012C07Rik; NEDD4.2; Nedd4-2; Nedd4b
  • Other Desigations E3 ubiquitin-protein ligase NEDD4-like; HECT-type E3 ubiquitin transferase NED4L; neural precursor cell expressed, developmentally down-regulated gene 4b
  • Gene Type protein-coding
  • Summary
    Enables sodium channel inhibitor activity and ubiquitin protein ligase activity. Acts upstream of or within several processes, including negative regulation of systemic arterial blood pressure; regulation of bicellular tight junction assembly; and regulation of ion transport. Predicted to be located in Golgi apparatus and endosome. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb segment; and retina. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 83814
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Nedd4l(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nedd4l expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Nedd4l expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Nedd4l expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Nedd4l expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Nedd4l expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nedd4l shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Nedd4l shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Nedd4l shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Nedd4l shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nedd4l CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Nedd4l CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Nedd4l CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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