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Vectors for Mouse Bckdhb

Gene Information

  • Offical Gene Symbol Bckdhb
  • Species Mouse (Mus musculus)
  • Offical Full Name branched chain ketoacid dehydrogenase E1, beta polypeptide
  • Other Aliases BCKDE1B; BCKDH E1-beta
  • Other Desigations 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial; branched-chain alpha-keto acid dehydrogenase E1 component beta chain
  • Gene Type protein-coding
  • Summary
    This gene encodes the beta chain of the branched chain alpha ketoacid dehydrogenase (Bckdh) complex. The encoded protein exists in a heterotetrameric complex containing the Bckdh alpha subunit to form the E1 catalytic component of Bckdh complex. The Bckdh complex catalyzes the oxidative decarboxylation of branched chain ketoacids to their corresponding acyl-CoA esters, during the catabolism of leucine, isoleucine and valine. In humans, certain mutations in this gene cause maple syrup urine disease. Alternative splicing results in multiple transcript variants encoding different isoforms. A pseudogene for this gene has been identified. [provided by RefSeq, Apr 2015]
  • NCBI Gene ID 12040
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Bckdhb(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Bckdhb expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Bckdhb expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Bckdhb expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Bckdhb expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Bckdhb expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Bckdhb shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Bckdhb shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Bckdhb shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Bckdhb shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Bckdhb CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Bckdhb CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Bckdhb CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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