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Vectors for Human RNASEH1

Gene Information

  • Offical Gene Symbol RNASEH1
  • Species Human (Homo sapiens)
  • Offical Full Name ribonuclease H1
  • Other Aliases H1RNA; PEOB2; RNH1
  • Other Desigations ribonuclease H1; ribonuclease H type II
  • Gene Type protein-coding
  • Summary
    This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 246243
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RNASEH1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNASEH1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RNASEH1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RNASEH1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RNASEH1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RNASEH1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNASEH1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RNASEH1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RNASEH1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RNASEH1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNASEH1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RNASEH1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RNASEH1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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