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Vectors for Human PPM1L

Gene Information

  • Offical Gene Symbol PPM1L
  • Species Human (Homo sapiens)
  • Offical Full Name protein phosphatase, Mg2+/Mn2+ dependent 1L
  • Other Aliases PP2C-epsilon; PP2CE; PPM1-LIKE
  • Other Desigations protein phosphatase 1L; PP2C epsilon
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
  • NCBI Gene ID 151742
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PPM1L(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1L expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PPM1L expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PPM1L expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PPM1L expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PPM1L expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1L shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PPM1L shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PPM1L shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PPM1L shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1L CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PPM1L CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PPM1L CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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